Dr Mohamed El-brolosy
Junior Fellow at the Harvard Society of Fellows
About
El-brolosy is a junior fellow at the Harvard Society of Fellows studying genetic adaptation. He obtained his PhD from Frankfurt University and the Max Planck Institute for Heart and Lung Research.
Current research
El-brolosy investigates the molecular mechanisms underlying genetic compensation to mutations, and its therapeutic potential for genetic diseases.
Future research vision
El-brolosy will Investigate the therapeutic potential of the phenomenon of transcriptional adaptation to mutations.
Key publications

Jiang, Z*, El-Brolosy, MA* et al. Parental mutations influence wild-type offspring via transcriptional adaptation. Science Advances, 2022.

El-Brolosy, MA et al. Genetic compensation triggered by mutant mRNA degradation. Nature, 2019.

El-Brolosy, MA et al. Genetic compensation: A phenomenon in search of mechanisms. PLOS Genetics, 2017.

Key awards

Bayer Pharmaceuticals PhD Award, German Society of Biochemistry and Molecular Biology.

Elisabeth-Gateff-Prize, German Genetics Society

Otto Hahn Medal, Max Planck Society.

30 under 30 list, Forbes (Europe – Science and Healthcare).

International Max Birnstiel Award, Institute of Molecular Pathology.